Hypersphere HealthPatient 3-D™ See it on your data

Multiple chronic conditions

AI-driven care management for multiple chronic conditions.

She looks stable on every chart. She isn’t. Patient 3-D sees how a person’s conditions compound — and acts before the admission does.

Runs beside everything you own. Replaces nothing.

As her chart sees her
RISK SCORE · MID-RANGE · NO FLAGS

Margaret, 71. Heart failure, kidney disease, diabetes — each one controlled. Three line items. Nothing due.

As Patient 3-D sees her
COMPOUNDING · NEPHROLOGY ≤ 48 H

Her heart failure is straining kidneys her diabetes is already damaging. The diuretic that keeps her breathing is pushing her kidneys down. Her readmission is three weeks away — and her chart has no flag for it.

America has an epidemic nobody scores.

100,000,000+Americans living with two or more chronic conditions4 in 10 adults · CDC
9 in 10older adults — and 6 in 10 young adults. Not a Medicare problem.Source: CDC / NCHS
$4.05Ta year — 90 cents of every healthcare dollar — on chronic and mental conditionsSource: CDC · America’s Health Rankings
14×the cost once a patient carries five. It doesn’t add. It compounds.Source: CDC / AHR

A patient with heart failure, kidney disease and diabetes is the most expensive person in American medicine — and on every instrument that scores her, she looks like three controlled conditions.

Twelve medications. Nineteen doses a day. One patient.

In 2005, researchers at Johns Hopkins described a 79-year-old woman with five ordinary conditions — osteoporosis, arthritis, diabetes, hypertension, COPD — and followed the national guideline for each one. The guidelines, each written for a single disease, prescribed her twelve medications, nineteen doses a day, at five different times, with interactions no guideline had considered.

Twenty years later nothing has changed in the architecture. Charlson, Elixhauser, ACG, the CMS risk model — every instrument a physician or a CFO relies on adds conditions up. The one that admits conditions interact models five pairs. Five.

Medicine knows her conditions compound. Her chart doesn’t.

Boyd et al., JAMA · CMS-HCC relative-factor tables
Medication list · five guidelines appliedF, 79
12medications
19doses a day
5times a day
Osteoporosisguideline one
Osteoarthritisguideline two
Type 2 diabetesguideline three
Hypertensionguideline four
COPDguideline five

Each guideline written for one disease. She did not have one disease.

We built the instrument that sees what her chart cannot.

Patient 3-D adds the dimension medicine always knew and no instrument computed: how a patient’s conditions interact. Breadth × severity × interaction. Immutable and changeable — age, genetics, behavioral health, social determinants, medications, utilization — resolved into one picture of one person.

1 in 37patients with multiple conditions is compounding in a way no risk score can represent
1 in 58looks stable on every chart — and is on a trajectory the chart cannot see

This is not a higher score. It is the person the additive instrument could not see — found before the admission, not after.

59clinical severity instruments
65named syndromes
177compounding patterns
221conditions
24,310interaction pairs
3.8 µsper patient10
391,702,652resolvable patient configurations9

From the first score to the closed loop. Already paid for.

One patient’s path through the platform. Every step is a service already covered — activated for the patients who need it.

  1. She is seen.

    Her record arrives — the same record everyone had. The engine reads her three conditions as one compounding trajectory and names what no single-disease guideline was watching for.

  2. Her physician opens the chart.

    The protocol is already there: nephrology within 48 hours, a medication reconciliation, a transitional-care visit — fired by her interactions, routed to the roles that own them, documented with the codes that pay for them.

  3. Her home is connected.

    A monitoring kit chosen for her profile, not a generic box. Her blood pressure, weight and glucose reach a nurse before they reach an emergency room.

  4. Her care team runs on one queue.

    A Care Captain, a nurse triage line that never closes, a community health worker for the ride she couldn’t get — dispatched by the protocol, not by whoever noticed first.

  5. Her care is documented, billed and closed.

    Each action acknowledged, completed or disputed, date-stamped. Chronic care management, remote monitoring, transitional care — services already covered, now activated.

  6. Her outcomes are reported — and audited by someone who isn’t us.

    Every figure traces to an engine run. The audit lives in a store we write and cannot touch.

  7. She stays home.

    That’s the outcome. Everything else is the machinery.

  8. Fourteen agents run this loop — intake to reporting — each with a trigger, a success condition and a rule for what it does when it can’t succeed: it withholds; it never estimates.

    Watch it run →

Measured, not promised.

Cohort 01 · Academic health system2.49 million lives · two regions
Compounding-active
31%
Re-ranked
17%
Reproducible
to the commit
Install · sealed containerNothing installed but Python and Node
Checksum
verified
Enforced gates
40 of 40
Served
one unattended run

It replaces nothing you own.

Reads Epic. Reads Cerner. Hands the protocol back into the workflow your clinicians already use. No waiver, no new code, no new payment model — the services were always there. We tell you which patients turn them on.

Built by people who ran the systems it fixes.

Twenty years inside government health programs. PMO leadership across twenty-five-plus health plan launches. Delivered with ELEKS, InterSystems and Rhapsody.

Working now with an academic health system, a Midwest county, two state Rural Health Transformation programs, a college of medicine and a regional Blue plan.

The clinical bench · fourteen seats

Two former health-plan chief medical officers · A life and health reinsurance actuary · A practicing family physician and clinical informaticist · A 40-year quality physician executive · A clinical pharmacist · Chronic-care, digital-health and consumer-activation founders · A nurse leader who cut readmissions by a third · Payer-quality, commercialization and market-strategy operators

Named seats and credentials available on request.

How it starts.

A proof of value: one extract under a data use agreement and your clinicians’ judgment, with nothing installed on your side. In production, Patient 3-D runs inside your environment, and your data never leaves it.

How Patient 3-D connects to your EHR →

  1. One extract under a data use agreement, delivered once.

    A flat-file extract you already know how to produce, limited to the fields the analysis needs. We send the column spec; you send the file once.

  2. A sealed U.S. environment.

    The proof of value runs in a sealed environment in the United States, with no connection to your systems.

  3. Your clinicians at the review table.

    Your named clinical reviewers see every figure before any figure is released.

  4. Results in weeks.

    Your population measured in three dimensions — what each patient has, how severe, how it compounds. Weeks, not a program.

  5. Destroyed, with a certificate.

    When the work ends the environment is destroyed, and you receive a certificate of destruction.

Every American with multiple chronic conditions, seen in three dimensions, by the end of the decade.

A flat-file extract, a sealed environment, your clinicians at the review table, results in weeks.

Sources

  1. 100,000,000+ adults with two or more chronic conditions; 129M with at least one; 6 in 10 and 4 in 10 adults. Source: CDC, About Chronic Disease (cdc.gov/chronic-disease/about); CDC, stacks.cdc.gov/view/cdc/61396.
  2. Prevalence by age: 9 in 10 older adults; 8 in 10 in midlife; 6 in 10 young adults. Source: CDC/NCHS; prevalence by age, PubMed Central.
  3. 90% of $4.5T in annual health spending; $4.05T. Source: CDC, via America’s Health Rankings (United Health Foundation) analysis of BRFSS.
  4. 14× spend at five or more conditions; 2.5×, 6× and 13.5× at lower counts. Source: CDC; America’s Health Rankings.
  5. Boyd CM et al., JAMA 2005;294:716-724: 12 medications, 19 doses a day.
  6. CMS 2024 Rate Announcement, relative-factor tables: five disease-interaction terms.
  7. “1 in 3”: share of scored lives with an active compounding interaction. 35.7% in a synthetic cohort calibrated to a Midwest county; 31.2% and 31.9% in the two regions of a synthetic cohort calibrated to an academic health system. Source: Tier Zero output files.
  8. “1 in 5”: share of scored lives that rank higher under compounding than under additive scoring. 21.3% in the Midwest county cohort; 17.4% and 18.2% in the two regions of the academic health system cohort.
  9. Canonical engine set: 221 conditions; 65 named syndromes; 24,310 interaction pairs, C(221,2); 59 clinical severity instruments; 177 compounding patterns; 391,702,652 resolvable configurations; 27 action rules, 74 codes, 66 measures, 29 citations. Source: HPDM engine registry at commit aa2c933.
  10. Timing: kernel score() median 3.792 µs, p95 6.0 µs, about 253,756 patients per second over 120,000 condition sets; POST /score median 3.977 ms, p95 4.927 ms. Source: timing run at engine commit 519c086.
  11. Academic health system cohort, two regions: 2,299,052 lives, 2,088,115 scored, 911,181 care-management eligible; and 190,387 lives, 172,318 scored, 77,544 care-management eligible. Compounding-active 31.2% and 31.9%; re-ranked 17.4% and 18.2%. Source: Tier Zero output at engine commit aa2c933, run 31814e1. Synthetic cohort; no PHI.
  12. Midwest county cohort, all-payer: 158,867 covered lives; 151,181 scored; 78,630 clinically eligible; 35.7% compounding-active; 21.3% re-ranked; median multiplier 1.62×; p95 4.5×. Regenerated at engine commits 7bee207, 66b761a, c0e67fc, bd0e899 and f6a76ad; 492 values asserted, 0 moved. Synthetic cohort built from public census data; no PHI.
  13. Gates: 48 automated gates, 40 enforced. Source: CI run 20261009.2, commit fe9bbb7.
  14. Acceptance run: a release archive installed, gated and run in a container holding only Python and Node, in one unattended command that exited clean. Source: PC-01 acceptance log, engine commit 31814e1.
  15. Clinical bench: seats and credentials as stated by each seat holder. Named seats and credentials are available on request.